Complete List of Published Work in MyBibliography

2019 - Present (University of Iowa years)

  • Jagadish, S., Czech, MT., Zimmerman, MB., Glykys, J. Epilepsy Incidence and Developmental Outcomes After Early Discontinuation of Antiseizure Medication in Neonatal Hypoxic-Ischemic Encephalopathy. Pediatric Neurology. Jan 11. https://doi.org/10.1016/j.pediatrneurol.2024.01.009

  • Liddiard GT, Suryahvanshi PS, Glykys J. Enhancing GABAergic tonic inhibition reduces seizure-like activity in the neonatal mouse hippocampus and neocortex. Journal of Neuroscience 4 January 2024, e1342232023; DOI: https://doi.org/10.1523/JNEUROSCI.1342-23.2023

  • Islam MS, Suryavanshi P, Baule SM, Glykys J*, Baek S*. A Deep Learning Approach for Neuronal Cell Body Segmentation in Neurons Expressing GCaMP using a Swin Transformer. eNeuro. 2023 Sep 13; ENEURO.0148-23.2023. PMID: 37704367. [*, Corresponding authors]

  • Takezawa, Y., Langton, R., Baule, SM., Zimmerman, MB., Baek, S., Glykys, J. Role of NKCC1 and KCC2 during hypoxia-induced neuronal swelling in the neonatal neocortex. Neurobiology of Disease. 2023. PMID: 36706928. DOI: 10.1016/j.nbd.2023.106013
  • Langton R, Sharma S, Tiarks GC, Bassuk AG, Glykys, J. (2022).Lacosamide decreases neonatal seizures without increasing apoptosis. Epilepsia.  PMID: 36168798. doi: 10.1111/epi.17423
  • Madathil, S., Matsumoto, S., Mathews, KD., Glykys, J. (2021). Central Nervous System Infections Due to Streptococcus anginosus Group: A Single-Center Case Series. J. Child Neurol.  Dec 1;8830738211052132.  doi: 10.1177/08830738211052132.
  • Sturgeon M., Langton R., Sharma S., Cornell R., Glykys J.*, Bassuk AG* (2021). The opioid antagonist naltrexone decreases seizure-like activity in genetic and chemically induced epilepsy models.  Epilepsia Open. Sep; 6(3):528-538.  [*, Corresponding authors]
  • Rahmati R., Normoyle K., Glykys J., Dzhala V., Lillis K., Kahle KT., Raiyyani, R.,  Jacob T., Staley, KJ. (2021). Unique actions of GABA arising from cytoplasmic chloride microdomains.  J. Neurosci. Jun 9;41(23):4957-4975.
  • Tong, L., Langton, R., Glykys, J.*, Baek, S.* (2021)ANMAF: an automated neuronal morphology analysis framework using convolutional neural networks. Sci. Rep. Apr 14;11(1):8179.  [*, Corresponding authors]
  • Cole M., Zhorne L., Glykys J. Atypical Presentation of Primary Stabbing Headache in a Patient With Type 3 Gaucher Disease. (2021). Pediatric neurology. 13;116:57-58.

2007-2019 (Massachusetts General Hospital/Harvard University years)

  • Glykys, J., Duquette, E., Rhamati, N., Duquette, K., Staley, KJ. (2019). Mannitol decreases neocortical epileptiform activity during early brain development via cotransport of chloride and water. Neurobiol Dis. Feb 1;125:163-175.
  • Glykys, J., Dzhala, V., Egawa, K., Kahle, KT., Delpire, E., Staley, K. (2017).Chloride Dysregulation, Seizures, and Cerebral Edema: A Relationship with Therapeutic Potential.Trends Neurosci. May;40(5):276-294
  • Glykys, J., Staley KJ. (2016). Developmental Decrease of Neuronal Chloride Concentration Is Independent of Trauma in Thalamocortical Brain Slices. PLoS One.Jun 23;11(6):e0158012. 
  • Glykys, J., Staley, J. (2015). Diazepam effect during early neonatal development correlates with neuronal Cl−. Ann Clin Transl Neurol.Oct 27;2(12):1055-70. 
  • Benowitz I, Cohen AR, Glykys JC, Gorstein SV, Burns MM, Miller ES. (2015) An Altered, Unresponsive Teenager in the Emergency Department. J Emerg Med. Jan;50(1):116-20. doi: 10.1016/j.jemermed.2015.09.023. Epub 2015 Oct 21.
  • Glykys J, Dzhala V, Egawa K, Balena T, Saponjian Y, Kuchibhotla KV, Bacskai BJ, Kahle KT, Zeuthen T, Staley KJ. (2014). Response to Comments on “Local impermeant anions establish the neuronal chloride concentration.” Science.345 (6201):1130
  • Glykys J*, Dzhala V*, Egawa K*, Balena T, Saponjian Y, Kuchibhotla KV, Bacskai BJ, Kahle KT, Zeuthen T, Staley KJ. (2014). Local impermeant anions establish the neuronal chloride concentration. Science.343(6171):670-5
    • Stafstrom, CE.  Constrained by The Matrix: Will Chloride Ions Be Set Free? (2015) Epilepsy Currents: 15(2): 92-93.
    • Adler EM. Of pumps, protons, chloride gradients, and microvesicles at the immunological synapse. (2014). J Gen Physiol.143(4):417-8.
  • Dzhala VI*, Valeeva G*, Glykys J*, Khazipov R, Staley K.(2012) Traumatic Alterations in GABA Signaling Disrupt Hippocampal Network Activity in the Developing Brain. J Neurosci.32(12):4017-4031  
  • Dzhala VI*, Kuchibhotla KV*, Glykys JC, Kahle KT, Swiercz WB, Feng G, Kuner T, Augustine GJ, Bacskai BJ, Staley KJ.(2010). Progressive NKCC1-dependent neuronal chloride accumulation during neonatal seizures. J Neurosci. 30(35):11745-61.
  • Glykys, J.*, Dzhala, VI.*, Kuchibhotla, KV., Feng, G., Kuner, T., Augustine, G., Bacskai, BJ., Staley, KJ.(2009). Differences in cortical versus subcortical GABAergic signaling: a candidate mechanism of electroclinical uncoupling of neonatal seizures. Neuron.63(5):657-72. (Cover of the issue)
    • Better Understanding of Newborn Seizures Leads to Potential New Treatment. NINDS News Articles, Oct 30, 2009

2002-2007 (UCLA years)

  • Glykys, J., Mann, E.O., Mody, I. (2008). Which GABAA receptor subunits are necessary for tonic inhibition in the hippocampus?. J. Neurosci.28(6):1421-1426.
  • Glykys, J., Mody, I. (2007). Activation of GABAA receptors: views from outside the synaptic cleft. Neuron.56(5):763-70. 
  • Glykys, J., Mody, I. (2007). The main source of ambient GABA responsible for tonic inhibition. J. Physiol.582(Pt 3):1163-78.
    • Paper achieved Century Citation Status (100 citations within ten years of publication in April 2015). The Journal of Physiology.
  • Mody, I., Glykys, J., Wei W.(2007).A new meaning for “Gin & Tonic”: tonic inhibition as the target for ethanol action in the brain. Alcohol.41(3):145-53. 
  • Glykys, J. *, Peng, Z.*, Chandra, D., Homanics, G.E., Houser, C.R., Mody, I. (2007). A novel naturally occurring GABAA receptor subunit partnership with high sensitivity to ethanol. Nat. Neurosci.10(1): 40-8
  • Klaassen, A.*, Glykys, J.*, Maguire J.*, Labarca C., Mody I., Boulter J. (2006). Seizures and enhanced cortical GABAergic inhibition in two mouse models of human autosomal dominant nocturnal frontal lobe epilepsy. PNAS. 103(50): 19152-7
  • Glykys, J., Mody, I. (2006). Hippocampal network hyperactivity after selective reduction of tonic inhibition in GABAAreceptor a5 subunit-deficient mice. J Neurophysiol.95(5): 2796-807.

(Venezuela years)

  • Gutiérrez, CI., Urbina, M., Obregón, F., Glykys, J., Lima, L. (2003). Characterization of Tryptophan high affinity transport system in pinealocytes of the rat. Day-night modulation.Amino Acids.25:95-105
  • Glykys, J., Guadama, M., Marcano, L., Ochoa, E., Eblen-Zajjur, A. (2003). Inflammation induced increase of fluoride resistant acid phosphatase (FRAP) in the spinal dorsal horn in rats. Neurosci Lett. Feb 13;337(3):167-9

BOOK CHAPTERS

  1. Glykys, J and Jones, Robin M. (2013). Pediatric Neurology in the Emergency Department. Chapter 4. In: Handbook of Pediatric Neurology.1stEd. Editors: Sims K., Peters, J., Musolino, P., Elibol, MZ. Lippincott Williams & Wilkins
  2. Glykys J, Sims KB. (2017). The Neuronal Ceroid Lipofuscinosis Disorders. Chapter 48. In: Swaiman's Pediatric Neurology. 6thEd. Editors: Swaiman KF, Ashwal S, Ferriero DM, Schor NF, Finkel RS et al. Elsevier.
  3. Berdichevsky, Y., Glykys, J., Dzhala, V., Lillis, K Staley, KJ. (2017). Organotypic Hippocampal Slice Cultures as a Model of Posttraumatic Epileptogenesis. Chapter 21. In: Models of Seizures and Epilepsy. 2ndEd. Editors: Pitkänen, A., Buckmaster, P., Galanopoulou, A., Moshé, SL. Elsevier.